This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 28 June – 4 July 2025 and includes updates on influenza A(H5N1), Middle Eastern Respiratory Syndrome (MERS), SARS-CoV-2, updates on respiratory virus epidemiology in the EU/EEA, poliomyelitis, Crimean-Congo haemorrhagic fever, West Nile virus infection, and chikungunya.